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0Title:
Toward Sustainable Carbon Capture and Utilization via Synthetic Biology
Astract:
Their mission is to solve the carbon dioxide problem by using technologies and concepts of synthetic biology which follows the steps of design, build, test and learn. Till now, ribulose-1,5-bisphosphate carboxylase/oxygenase, (RuBisCO) is the most effective enzyme for carbon dioxide uptake. Therefore, they developed the RuBisCO-equipped Escherichia coli to boost carbon dioxide assimilation and coupled with different enzymes for high-end chemicals. On the other hand, they have explored many genes, from pyridoxal kinase (pdxY), carbonic anhydrase (CA), and chaperone protein (GroELS), which were integrated into Chlamydomonas reinhardtii or applied using CRISPRa/i technology in Chlorella sorokiniana, thus enhancing carbon capture and utilization in microalgae.
Personal Profile:
Professor I-Son (Grace) Ng currently serves in the Department of Chemical Engineering at National Cheng Kung University (NCKU) since 2014 and is a leading scholar in synthetic biology. Prior to joining NCKU, she served at Xiamen University from 2010 to 2014. Under her guidance, NCKU student teams have earned 7 gold medals and the 2019 World Championship at iGEM. She received the University Innovation and Social Responsibility Teaching Excellence Award for four consecutive years (2020 – 2023), the Research Excellence Award in NCKU (2021), the Outstanding Female Chemical Engineer Award from Taiwan Institute of Chemical Engineers (2022), and from the Biotechnology and Biochemical Engineering Society of Taiwan (2023), Outstanding Research Award in National Science and Technology Council (NSTC, 2024). Since 2020, she has been ranked among the top 2% of scientists worldwide.
