843-Fatigue-Resistant Myoneural ActuatorsPaper Talk

843-Fatigue-Resistant Myoneural Actuators

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Researchers have developed a myoneural actuator (MNA) designed to improve the performance of implantable biohybrid systems. By replacing a muscle’s native motor nerve with a sensory nerve, the scientists successfully redirected control from the central nervous system to a computer-controlled interface. This surgical innovation creates a more uniform axonal distribution, which enhances fatigue resistance by 260% compared to natural muscle. The system also utilizes a reversible nerve block to prevent unwanted electrical signals from reaching the brain during operation. Practical tests in rodent models demonstrated that this technology can successfully drive neuroprosthetic interfaces and emulate organ mechanics, such as intestinal contractions. Ultimately, the MNA provides a self-sustaining, biocompatible solution for restoring biological functions and providing sensory feedback in bionic devices.

References:

  • Song H, Herrera-Arcos G, Friedman G N, et al. A myoneural actuator with engineered biophysics for implantable biohybrid systems[J]. Nature Communications, 2026, 17(1): 2584.