瑞典STEM-PD临床试验将胚胎干细胞衍生的多巴胺神经元移植入患者大脑。首例患者托马斯术后一年恢复嗅觉，能滑冰、滑雪等，大幅减药。该疗法或重建神经回路，改变帕金森治疗范式。

参考文献：

1. Skåne University Hospital. First patient treated with stem cell-derived nerve cells in Parkinson's disease STEM-PD trial. 2023.

1. Kirkeby A, et al. Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD. Cell Stem Cell. 2023.

1. Swedish Medical Products Agency. Clinical trial authorisation for STEM-PD (EudraCT 2021-001366-38). 2022.

1. Gesine Paul-Visse, et al. STEM-PD I/IIa clinical trial protocol. Lund University. 2022.