今天3分钟我们来聊聊打一年瘦17%，停一年胖回2/3：减肥神药停药后身体发生了什么

本期「源于细胞」科普播客拆解大家最关心的两个司美格鲁肽核心问题：结合多项硬核临床研究讲透停药后快速反弹的底层机制，澄清减重掉肌肉的真实误区，同时给出抗阻训练+足量蛋白的实操应对方案，帮你科学用药避坑。

参考文献：

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2. West S, et al. Weight regain after cessation of medication for weight management: systematic review and meta-analysis. BMJ. 2026;392:e085304. DOI: 10.1136/bmj-2025-085304

3. Prado CM, et al. Body composition phenotypes and obesity revisited（GLP-1身体成分综述）. Lancet Diabetes Endocrinol. 2024（STEP 1 DXA子研究：瘦组织占减重约39-40%）

4. Alissou M, Demangeat T, et al. Impact of semaglutide on fat mass, lean mass and muscle function: the SEMALEAN study. Diabetes Obes Metab. 2025. PMC12673431

5. Lundgren JR, et al. Healthy weight loss maintenance with exercise, liraglutide, or both combined. N Engl J Med. 2021;384:1719-1730. DOI: 10.1056/NEJMoa2028198

6. Aronne LJ, et al. Continued tirzepatide for maintenance of weight reduction: SURMOUNT-4 RCT. JAMA. 2024;331(1):38-48. DOI: 10.1001/jama.2023.24945